Wednesday, May 8, 2013

Acyclovir Pharmacology and Indication

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Acyclovir Pharmacology and Indication
Artikel-bahasainggris.blogspot.com - Acyclovir is acyclic purine nucleoside analogue active against herpes simplex virus, varicella zoster, Epstein-Barr virus and cytomegalovirus. In the cell, undergo phosphorylation acyclovir acyclovir triphosphate into an active form that inhibit the herpes simplex virus DNA polymerase and viral DNA replication, thereby preventing viral DNA synthesis without affecting normal cell processes.

Acyclovir Pharmacology
Acyclovir is an antiviral agent highly active in vitro against herpes simplex virus (HSV) types I and II, and varicella zoster virus. Upon entry into the infected cell, the phosphorylated form of the active compound Acyclovir Acyclovir trifosfate. The initial phase of the process depends on the enzyme thymidine kinase viral-coded. Acyclovir trifosfate act as inhibitors and as a false substrate for the herpes-specified DNA polymerase which prevents viral DNA synthesis without affecting normal cellular processes.

Treatment of herpes simplex virus infections of the skin and mucous membranes including initial and recurrent genital herpes / recurrent, herpes zoster (shingles / shingles / shingles). Preventing recurrence of herpes simplex infections in patients with strong immune systems. Preventing herpes simplex infection in patients with poor immune systems.

Another acyclovir pharmacology is a treatment of herpes simplex virus infections of the skin and mucous membranes including initial and recurrent genital herpes / recurrent, herpes zoster (shingles / shingles / shingles); preventing recurrence of herpes simplex infections in patients with strong immune systems; preventing herpes simplex infection in patients with poor immune systems.

Acyclovir Indication
Acyclovir indication such as treatment of herpes simplex virus on the skin and mucus membranes, including initial and recurrent genital herpes; treatment of herpes zoster and varicella infections; treatment of infections caused by the herpes simplex of the skin and mucous membranes including initial and recurrent genital herpes, herpes simplex infection prevention in immuno-compromised patients; treatment of herpes zoster infection.

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